Synthesis and characterisation of α-carboxynitrobenzyl photocaged l-aspartates for applications in time-resolved structural biology
Zaitsev-Doyle, John J.; Puchert, Anke; Pfeifer, Yannik; Yan, Hao; Yorke, Briony A.; Müller-Werkmeister, Henrike M.; Uetrecht, Charlotte; Rehbein, Julia; Huse, Nils; Pearson, Arwen R.; Sans, Marta
2019

Files

Abstract

We report a new synthetic route to a series of α-carboxynitrobenzyl photocaged L-aspartates for application in time-resolved structural biology. The resulting compounds were characterised in terms of UV/Vis absorption properties, aqueous solubility and stability, and photocleavage rates (τ = μs to ms) and quantum yields (φ = 0.05 to 0.14).

Details

Title Synthesis and characterisation of α-carboxynitrobenzyl photocaged l-aspartates for applications in time-resolved structural biology
Author Zaitsev-Doyle, John J.
Puchert, Anke
Pfeifer, Yannik
Yan, Hao
Yorke, Briony A.
Müller-Werkmeister, Henrike M.
Uetrecht, Charlotte
Rehbein, Julia
Huse, Nils
Pearson, Arwen R.
Sans, Marta
Affiliation EuXFEL guest, Other
Author Group Sample Environment
Topic
Scientific Area
Imprint Royal Society of Chemistry, 2019
Date 2019
Publication Information
RSC Advances, 9 (15), 8695-8699 (2019)
Related external records DOI: https://doi.org/10.1039/C9RA00968J
Content Type Articles
Language English
External Website https://pubs.rsc.org/en/content/articlelanding/2019/ra/c9ra00968j#!divAbstract
Record Appears in Groups > Scientific instruments and equipment > Sample Environment
Topics > External experiments
Types > Articles
Years > 2019

PDF

Statistics

from
to
Export
Download Full History