A Hard X-Ray Self-Seeding (HXRSS) setup will be soon commissioned at the European XFEL. It relies on a two-chicanes scheme to deal, in particular, with the high pulse repetition rate of the facility. In this contribution we review the physics choices made at the design stage and the expected performance of the setup. We will also focus on the description of the hardware installations made at the SASE2 line of the European XFEL.