Record Details

Title:
Instrumentation and Software Support for X-Ray Radiation Sensitivity Studies of DNA Crystals
Affiliation(s):
EuXFEL staff, Other
Author group:
Control and Analysis Software
Topic:
Abstract:
As a revival of κ goniometry, Brockhauser et al.’s mini- κ goniometer head enables the reorientation of a macromolecular crystal for optimal X-ray data collection e.g. measuring Bijvoet pairs without the systematic error of radiation dose differences. Current third generation synchrotrons are producing more than enough flux density for MX experiments. Hence, the limitation for solving big complex structures is radiation damage. While κ goniometry can be used for minimising this problem by careful reorientation of the samples, it also supports systematic studies of radiation damage effects. The purpose of this work is to study the sensitivity of DNA crystals and optimise data collection methodologies. As well as sample reorientation, we also focus on the positive effects of off-axis data collections.
Imprint:
2018
Language(s):
English
Conference information:
12th New Opportunities for Better User Group Software Conference , Upton, 2018-10-22, 2018-10-26, NOBUGS 2018


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 Record created 2019-02-25, last modified 2019-02-25

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