Record Details

Title:
Sorting algorithms for single-particle imaging experiments at X-ray free-electron lasers
Affiliation(s):
EuXFEL staff, Other
Author group:
Theory
Keyword(s):
Topic:
Scientific area:
Abstract:
Modern X-ray free-electron lasers (XFELs) operating at high repetition rates produce a tremendous amount of data. It is a great challenge to classify this information and reduce the initial data set to a manageable size for further analysis. Here an approach for classification of diffraction patterns measured in prototypical diffract-and-destroy single-particle imaging experiments at XFELs is presented. It is proposed that the data are classified on the basis of a set of parameters that take into account the underlying diffraction physics and specific relations between the real-space structure of a particle and its reciprocal-space intensity distribution. The approach is demonstrated by applying principal component analysis and support vector machine algorithms to the simulated and measured X-ray data sets.
Imprint:
International Union of Crystallography, 2015
Journal Information:
Journal of Synchrotron Radiation, 22 (6), 1345-1352 (2015)
Related external records:
Language(s):
English


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 Record created 2018-07-13, last modified 2019-08-01

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