Record Details

Title:
Three-Dimensional Reconstruction of the Giant Mimivirus Particle with an X-Ray Free-Electron Laser
Abstract:
We present a proof-of-concept three-dimensional reconstruction of the giant mimivirus particle from experimentally measured diffraction patterns from an x-ray free-electron laser. Three-dimensional imaging requires the assembly of many two-dimensional patterns into an internally consistent Fourier volume. Since each particle is randomly oriented when exposed to the x-ray pulse, relative orientations have to be retrieved from the diffraction data alone. We achieve this with a modified version of the expand, maximize and compress algorithm and validate our result using new methods.
Imprint:
College Park, Md., APS, 2015
Journal Information:
Phys. Rev. Lett., 114, 9, 098102 (2015)
ISSN:
0031-9007
1079-7114
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Language(s):
English
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 Record created 2016-10-11, last modified 2017-08-31

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